UCB35625, initially identified as a high affinity unbiased antagonist of CCR3 and CCR1, was subsequently found to be an agonist of CCR2 and CCR5, making it prohibitively complex for studies35, 36

UCB35625, initially identified as a high affinity unbiased antagonist of CCR3 and CCR1, was subsequently found to be an agonist of CCR2 and CCR5, making … Continue reading UCB35625, initially identified as a high affinity unbiased antagonist of CCR3 and CCR1, was subsequently found to be an agonist of CCR2 and CCR5, making it prohibitively complex for studies35, 36